Charles Handfield-Jones was born at Liverpool, the son of a retired naval captain, and was educated at Rugby under Dr. Arnold, at St. Catherine’s College, Cambridge, and at St. George’s Hospital. He graduated as B.A. in 1840 and M.B. in 1843. In his early career, he devoted himself to a research into the minute anatomy of the liver, and for this, at the early age of thirty-one, he was elected a Fellow of the Royal Society. In the next year he was appointed to the staff of the newly-founded St. Mary’s Hospital and quickly earned a reputation as a learned, careful, and hardworking physician. He remained interested in pathology and, with Sieveking, wrote a Manual of Pathological Anatomy (1854), which became a well-known textbook in its day. At the Royal College of Physicians, he delivered the Lumleian Lectures in 1865 and became a Censor and, in 1888, Vice-President. He married Louisa, daughter of Captain Holt, and had two sons. He died in London.

G H Brown

[B.M.J., 1890; D.N.B., xxx, 91; Al.Cantab., iii, 594]